I believe in minimalist care when it comes to vaccinations, www.hemopet.org is a great source of information.
I do not recommend the lepto vaccine for Great Dane puppies, giving this vaccine is often linked to HOD cases.
should be given by a licensed veterinarian, I do not recommend ordering vaccinations from any feed stores as they are not always kept cooled to the proper temperatures.
I do not ever
do more then one vaccination at a time (meaning doing bordatella, rabies and DHPP all in one visit) Also we recommend to wait to give the rabies vaccination until 6 months of age, and never with any other vaccines.